Thursday, August 3, 2017

Know Your Terpenoids : Pinene



Ok, now let me introduce this Terpenoid as my most favorite of the terpenes, Pinene. I am a sufferer from both the great pains of osteoarthritis and rheumatoid arthritis.  I live now in Las Vegas, it has the "dry heat" which helps with arthritis ( or "Arthur" as my mother always called it ).  I am originally born and raised in Virginia and let me just say , I do NOT miss the weather.  I feel terrible for anyone suffering from "Arthur" and having to deal with it in that humidity. So ... for those of you looking towards the cannabis medicine or already enjoy the plant this is most definitely a Terpenoid to look for!  

It's a major constituent of turpentine and is also found in high amounts in pine trees, rosemary and cannabis.  The characteristic scent in pine trees main terpene is Pinene.  In fact, pinene is the most commonly found terpene in the world!  Pinene has two main isomers, alpha- and beta-pinene, alpha-pinene is the dominant one that is found in cannabis.  


PINENE BREAK DOWN




Formula : C10H16

Molecular Mass : 136.23404 g/mol

Boiling Point : 155° C (311° F)

Lethal Dose (LD50) : 3700mg/kg for mice (Compare to Nicotine : for mice - 50 mg/kg, for humans - 0.5-1 mg/kg)

Aroma : Pine

Effects : 

Alertness, memory retention, counteracts some THC effects

Medical Value and Therapeutic Uses

Antiseptic - Asthma **
Analgesic - Relieves pain.
Antibacterial - Slows bacterial growth.
Anti-inflammatory - Reduces inflammation systemically.
Anti-Proliferative - Inhibits cancer cell growth. 

Antioxidant - Prevents oxidation damage to other molecules in the body.


Found In High Levels in Cannabis Strains : Blue Dream, Jack Herer, Chemdawg, Bubba Kush, Trainwreck, Super Silver Haze, and this weeks favorite photographed from HOPE products. Also remember that Happy Fact, when confused just look at the prescription label.  


Also Found In : Pine Needles, Rosemary, Parsley, Basil and Dill  **So if you are a sufferer of arthitsis and/or chronic pain, UP your intake and cook or choose your dishes consisting of rosemary, parsley, basil.


**Look in my tabs under THE HAPPY CHEF for recipes to help you when Arthur comes to visit. (:


Like many terpenes and cannabinoids, pinene is both an anti-inflammatory and analgesic , making it useful for a sufferer of chronic pain.  Pinene helps fight cancer by promoting apoptosis and being an inhibiter or to retard the spreading of cells.  Pinene is an antioxidant and even appears to aid in memory retention and there also is evidence that show that pinene can be a bronchodilator, increasing airflow to the lungs and helping with common conditions such as asthma. Patients whom suffer from asthma, if your method of consumption is inhaling cannabis, should look for strains high in pinene levels as it is better with your condition.



Pinene


Commonly found in higher concentrations in sativa strains like :

Blue Dream

Jack Herer

Chemdawg

Bubba Kush

Train wreck

Super Silver 

Haze 


If the names confuse you and you feel overwhelmed, don't worry, you are NOT ALONE!  As the saying goes "there's levels to this shit".  Look for the lab test , which is attached to your medicine on the packaging at any MED or REC state dispensary. It's always good to know the base knowledge of the indica verse sativa.  The names are given which determine of when they are harvested and the therapeutic effects.  This terpenoid can be found in both, so look on your prescription for that active compound, the higher levels I've found the best for pain.  



EXAMPLE OF PRESCRIPTION WITH SIGNIFICANT TRACES OF :
 alpha- and beta-pinene 
** IMPORTANT NOTE :  Each batch is subject to variable growing conditions, meaning NOT every batch of any given strain will have high levels of these terpenes.  The only way to be certain is through a lab's terpene analysis found on label of patients prescription.

I cooked my Medicinal Chew recipe with this batch of oil.  I made Mango Flavor! (delicious) --- catch my Instagram Stories and SnapChat Stories for videos and Behind The Scenes with me :





SNAPCHAT AT : @d.thc

Recipe is in Deliciously Dee's The Happy Chef Expert Cannabis Cookbook --> CLiCk FoR LiNk To ReCiPe


REVIEWS BELOW OF THIS RECIPE IN COOKBOOK

Screenshot From @EdibleDee Instagram Stories...reminding you where I am going with this particular strains compounds. 







Summary Of Case Studies Done On Pinene 


Studies :

- A study done in 2012, examined pinene's role in modulating inflammation in regards to Acute Pancreatitis, which is a complex inflammation disorder with an unknown cause.  The researchers then found that pinene does indeed have anti-inflammatory effects.  A 2011 study by Ethan Russo, a cannabis researcher who works with GW Pharmaceuticals ($GWPH), strengthened our understanding of how pinene works as an anti-inflammatory.  In 2014 pinene was reexamined to determine its anti-inflammatory abilities in humans and it was found to be a potential candidate to be a new anti-osteoarthritic drug - which means that cannabis rich in pinene can help with arthritis, but clearly this potential application needs further study.  FINALLY AN AID FOR ARTHUR! 

- This a 2007 study, which looked at pinene as a potential treatment for infectious endocarditis, found both alpha- and beta-pinene to be effective anti-microbial agents.  Pinene's anti-bacteria properties have been known about since the late 1980's, but have only seen further study in this past decade. (I wonder why, lol)  Another study around its anti-microbial properties, published in the January 2011 issue of Molecules found both alpha- and beta-pinene to be effective treatments for infectious bronchitis virus. This is fascinating as that viruses are not bacteria and are normally much harder to treat.  A 2012 study broadly examined pinene's told as a treatment for bacterial infections and found it to be effective, varying depending on the bacteria at play. 

Ethan Russo's 2011 study, Taming THC, warranted pinene's centuries of use as a folk remedy for asthma in showing that pinene works as a bronchodilator.  Pinene has not been shown to be risk free, shown in 2002 study, prolonged exposure can irritate the upper airway, despite this benefit to the upper respiratory tract.  Irritation seems relatively minor in relation to its benefits as a bronchodilator.  It was known as early as 2005 that pinene can inhibit acetylcholinesterase activity in the brain which has been shown to increase MEMORY retention.  Taming THC also explored pinene's ability to boost memory by acetylcholinesterase inhibition and found it to help with retention.

- This 2012 study on mice showed, for the first time, that pinene could slow the growth of tumors but could not identify the mechanism through which it worked.  A 2013 study looking at its effects on neuroblastoma cells found that pinene decreased proliferation of cancerous cells.  Most recently, we learned earlier this year that pinene was also helpful at mitigating the damage of hepatoma carcinoma and was viable as a potential anti-tumor drug. Justifying its aid to CANCER patients.



Thank you for reading!  Please COMMENT BELOW your thoughts and experiences with Pinene, would love to hear your stories or photographs you wish to share.  Also PLEASE SHARE and TAG a friend who may find this helpful! #BeTheChange #TheMoreYouKnowAboutCannabis #WeedScience 




Also check out these Terpenes - Know Your Terpenes : 














Also check -
SOURCES AND REFERENCE LINKS :

PubMed
PubChem
Linalool by Wikipedia
Linalool by leaf online
the Leaf online
https://www.leafly.com/news/cannabis-101/terpenes-the-flavors-of-cannabis-aromatherapy
https://www.ncbi.nlm.nih.gov/pubmed/22361888
https://link.springer.com/article/10.2478%2Fs11756-013-0230-2#page-1
http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01238.x/abstract
https://en.wikipedia.org/wiki/Terpenoid

About Me

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Birth name Danielle Russell, friends and colleagues call her Dee.  Dee has been making medibles or medicinal edibles with cannabis from 2006 to present.  In 2014 she published the first edition of her cannabis cookbook, The Happy Chef THC, including hip-hop album “The Prescription” from hip-hop artist and MMJ patient B-Real of Cypress Hill. The year 2015 was the year of legalization for medical marijuana for the state of Nevada.  Dee worked as a Canna Chef in the first licensed MMJ Production Kitchen in the state of Nevada located in the fabulous city of Las Vegas - she still continues to make her edibles for the patients in the state today.

Are edibles not your thing?  Maybe you had a bad edible cannabis experience?  Eat too much or not enough - trouble dosing?  Or - perhaps you enjoy cooking with the plant and/or have an interest in joining the cannabis industry as a Canna Chef in an MMK Production Lab.  In with case, HER LATEST CANNA COOKBOOK IS THE ONE YOU NEED!!  Check out her latest EXPERT CANNABIS COOKBOOK - Deliciously Dee The Happy Chef Expert Cannabis Cookbook.  (available on Amazon & iBooks)